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克隆類型：	Rabbit Polyclonal IgG
免疫原：	PhosphoPeptide derived from Hu C CBL around the phosphorylation site of Tyr700.
純化方式：	Immunogen affinity purified
緩沖液：	PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
產(chǎn)品描述：	This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder.
適用物種：	Hu, Mo, Rat, Dog, Pig, Cow, Hor,
應(yīng)用說明：	WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500
別　　名：	phospho-C CBL (Tyr700); CBL2 (phospho-Tyr700); CBL2 (phospho-Y700); p-CBL2 (Tyr700); p-CBL2 (Y700); C CBL; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B lineage lymphoma proto oncogene; CBL 2;E3 ubiquitin protein ligase CBL; Oncogene CBL2; Proto oncogene c CBL; RING finger protein 55; RNF55v Signal transduction protein CBL; CBL_Hu.
保存條件：	Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted.
標(biāo) 記物：	PLLABS公司可供應(yīng)生物素、辣根過氧化物酶、熒光素標(biāo)記抗體
產(chǎn)品說明：

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