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克隆類型：	Mouse Monoclonal Antibody
亞　　型：	mouse IgG1
免疫原：	A recombinant His-tagged protein fragment within the extracellular region of human DC-SIGN.
產(chǎn)品描述：	Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN (3). A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR are known to exisit. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
適用物種：	H
應用范圍：	E, WB, IHC
應用說明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
別　　名：	DC-SIGN; Dendritic cell-specific ICAM-3-grabbing nonintegrin 1
形　　態(tài) ：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
保存條件：	Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
產(chǎn)品鏈接：	http://www.abbiotec.com/antibodies/dc-sign-8b6-antibody
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產(chǎn)品說明：

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